COPD?

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Chronic obstructive pulmonary disease (COPD) is a chronic disease usually caused by exposure to noxious particles or gases like cigarette smoke. Symptoms like coughing, shortness of breath, and wheezing make it difficult to keep up with normal activities, but we’re working on new options. Learn about the cutting-edge study treatments being investigated near you.


1/5

Americans age 45 years and older has COPD. 1

37%

Women are 37% more likely to have COPD than men. 2

70%

of people with COPD say it limits physical activity. 3


COPD Clinical Trials

Learn about the newest COPD study treatments now being investigated, including cutting-edge study options available to clinical trial participants.

TrialSpark is now recruiting for a trial that tests the effectiveness of a cystic fibrosis drug on COPD symptoms.

Treatments Today

Many current treatments for chronic obstructive pulmonary disease (COPD) alleviate symptoms through bronchodilators, which relax the muscles around the airways.

8

Prescription treatments on the market in 2019.

Azithromycin

Azithromycin prevents exacerbations of COPD (acute bronchitis, pneumonia and influenza), but it isn't clear whether this is due to its antibiotic effect or its anti-inflammatory properties.

Availablity

RX

Brands

Azasite, Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax

Drug Class

Macrolide Antibiotics

Generic

Azithromycin

mayoclinic.org

Albuterol

Albuterol is a bronchodilator used to prevent and treat wheezing, difficulty breathing, chest tightness, and coughing caused by lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). Albuterol relaxes and opens the air passages to the lungs to make breathing easier. Albuterol belongs to class of drugs called short-acting beta-2- agonist bronchodilators. Available in different formulations, including oral syrups, inhalation powders, inhalation suspensions, and inhalation solutions.

Availablity

RX

Brands

ProAir HFA, ProAir RespiClick, Proventil HFA, Ventolin HFA, AccuNeb

Drug Class

Short-acting Beta2-agonists (Bronchodilators)

Generic

Albuterol

medlineplus.gov

Inhaled combination of Indacaterol and Glycopyrrolate

Utibron Neohaler, a combination medicine containing glycopyrrolate and indacaterol, is used to prevent airflow obstruction or bronchospasm in people with COPD. Glycopyrrolate is an anticholinergic. Indacaterol is a bronchodilator. These medications work by relaxing muscles in the airways to improve breathing. Utibron Neohaler should not be used in patients with asthma. Indacaterol may increase the risk of death in people with asthma, but the risk in people with COPD is not known.

Availablity

RX

Brands

Utibron Neohaler

Drug Class

Combination Inhaled Medicine: Beta2 Agonist + Anticholinergic

Generic

Glycopyrrolate and Indacaterol (Inhalation)

drugs.com

Inhaled Indacaterol

Inhaled indacaterol is a bronchodilator used to control wheezing, shortness of breath, coughing, and chest tightness caused by COPD. It works by relaxing and opening air passages in the lungs, making it easier to breathe. Indacaterol belongs to class of drugs called long-acting beta-2- agonists. It's available in a 75 mcg capsule.

Availablity

RX

Brands

Arcapta Neohaler

Drug Class

Long-acting Beta2-agonists (Bronchodilators)

Generic

Indacaterol

medlineplus.gov

Inhaled Ipratropium Bromide

Inhaled ipratropium is a bronchodilator used to prevent wheezing, shortness of breath, coughing, and chest tightness in COPD patients. It works by relaxing and opening air passages in the lungs, making it easier to breathe. Ipratropium belongs to a class of medications called short-acting anticholinergics.

Availablity

RX

Brands

Atrovent, Atrovent HFA

Drug Class

Short-acting Anticholinergics (Bronchodilators)

Generic

Ipratropium inhalation

mayoclinic.org

Roflumilast

Roflumilast is used in people with severe COPD to reduce the number of episodes or worsening of COPD symptoms. The drug works by decreasing inflammation (swelling) in the lungs. Roflumilast belongs to a class of drugs called phosphodiesterase inhibitors..

Availablity

RX

Brands

Daliresp

Drug Class

Phosphodiesterase-4 Inhibitors

Generic

Roflumilast

mayoclinic.org

Theophylline

Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.

Availablity

RX

Brands

Aerolate III, JR, and SR, Bronkodyl, Elixophyllin, Quibron-T/SR, Respbid, Slo-Bid Gyrocaps, Slo-Phyllin, T-Phyl, Theo-24, Theo-Dur, Theo-Time, Theo-X, Theobid, Theochron, Theoclear LA-130, Theoclear LA-260, Theolair, Theolair-SR, Theovent, Uni-Dur, Uniphyl

Drug Class

Methylxanthines

Generic

Theophylline

medlineplus.gov

Tiotropium

Tiotropium is a bronchodilator used to prevent wheezing, shortness of breath, coughing, and chest tightness in COPD patients. It works by relaxing and opening air passages in the lungs, making it easier to breathe. Tiatropium belongs to a class of medications called long-acting anticholinergics.

Availablity

RX

Brands

Spiriva, Spiriva Respimat, Spiriva HandiHaler, Spiriva Respimat 30 Dose, Spiriva Respimat 14 Dose, Spiriva Respimat 28 ACT, Spiriva Respimat 60 ACT

Drug Class

Long-acting Anticholinergics (Bronchodilators)

Generic

Tiotropium inhalation

mayoclinic.org

COPD In the News

From the latest relevant research and COPD expert interviews to personal stories and advice on managing your symptoms, here’s everything about COPD that’s making headlines.


FAQ

Whether you’re considering participating in a clinical trial or just looking for more information about COPD, we want to keep you informed about living with COPD, your treatment options, and the clinical trial process.


Join a COPD Community

Connect with others who have COPD to discuss your symptoms, experiences, treatment options, and more.

Stay updated on COPD.

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See if you qualify for a trial.

New study treatments that may help address your condition are being developed and investigated.

  1. Lung Health & Diseases: How Serious Is COPD (April 5, 2019) Link [1]

  2. Healthline, COPD: Facts, Statistics, and You,Link[2]

  3. Healthline, COPD: Facts, Statistics, and You, Link[3]

Updated June 2019