Psoriasis?

New study treatments may help you take charge of your skin.

The chronic inflammatory disease that affects skin and sometimes joints currently has no cure. But we’re working on giving you new options to help manage the symptoms of Psoriasis. Learn about the cutting-edge study treatments being investigated in your neighborhood.

~7.5

million people in the United States have Psoriasis ¹

1 in 3

people with psoriasis develop psoriatic arthritis, which affects the joints, tendons and ligaments ²

59%

of people living with Psoriasis say it's a large problem in their everyday lives ³

People can be really cruel, especially if they just don’t understand… I have to tell people it's not a disease you catch.

Patient

15 years with Psoriasis

I love clothes, so this has been a big impact for me… I don’t swim anymore. Everyone is in shorts, it’s so hot here and I’m parading around in jeans.

Patient

8 years with Psoriasis

Psoriasis Clinical Trials

Learn about the newest Psoriasis study treatments now being investigated, including cutting-edge options available to clinical trial participants.

TrialSpark is now recruiting for a trial that tests the effectiveness of a study drug for Psoriasis symptoms.

Learn more

Clinicaltrials.gov

Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis

4 weeks of adjunctive therapy of Enstilar® QD followed by 12 weeks QOD to patients with 2-10% BSA who are receiving etanercept or adalimumab for at least 24 weeks

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

LEO Pharma

Clinicaltrials.gov

Immunogenetic Profiling of Goeckerman Therapy in the Treatment of...

This study examines the effect of Goeckerman therapy (a combination of phototherapy and topical crude coal tar), crude coal tar alone, and phototherapy alone on the immunologic and genetic environment within...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

National Psoriasis Foundation

Clinicaltrials.gov

Linking Epidermal Barrier Function With Anti-Oxidant Defense...

Investigators will sample the skin and blood of patients with chronic skin conditions (including but not limited to atopic dermatitis (AD), contact dermatitis, hidradenitis suppurativa (HS), and psoriasis) to...

Trial Type

Observational

Sponsorship

University of Arizona

Clinicaltrials.gov

Apremilast Pregnancy Exposure Registry

The purpose of the Apremilast Pregnancy Exposure Registry is to monitor planned and unplanned pregnancies exposed to apremilast and to evaluate the safety of this medication relative to specified pregnancy...

Trial Type

Observational [Patient Registry]

Sponsorship

The Organization of Teratology Information Specialists

Clinicaltrials.gov

Efficacy and Safety Study of Apremilast (CC-10004) in Pediatric...

This is a Phase 3, multicenter, randomized, placebo-controlled, double-blind study of the efficacy and safety of apremilast (CC-10004) in pediatric subjects with moderate to severe plaque psoriasis. At least...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Celgene

Clinicaltrials.gov

The Psoriasis, Atherosclerosis, and Cardiometabolic Disease...

Background: - Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes. One disorder, psoriasis, is an...

Trial Type

Observational

Sponsorship

National Heart, Lung, and Blood Institute (NHLBI)

Clinicaltrials.gov

An Efficacy and Safety Study of Apremilast (CC-10004) in Subjects...

This Phase 3 multicenter, randomized, placebo-controlled, double-blind study is designed to evaluate the efficacy and safety of apremilast in subjects with moderate to severe genital psoriasis (modified sPGA-G...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Celgene

Clinicaltrials.gov

Psoriatic Arthritis and Psoriasis Treatment Decision Aid

The purpose of this study is to create and test a patient decision aid that facilitates the shared decision-making process when patients with psoriasis and/or psoriatic arthritis are starting or switching to a...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Pfizer

Clinicaltrials.gov

Evaluation of Add on Enstilar in Patients Using Otezla for Psoriasis

Patients with moderate to severe plaque psoriasis will be treated with Otezla BID. At week 8, non responders will be discontinued, partial responders will be given add-on Enstilar QD for 4 weeks and PASI 75...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Celgene Corporation

Clinicaltrials.gov

Enstilar® Foam in the Treatment of Chronic Plaque Psoriasis in...

This will be a single-center, randomized, double-blinded, vehicle-controlled clinical study to determine the efficacy of Enstilar® foam, a combination of calcipotriene and betamethasone dipropionate...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Icahn School of Medicine at Mount Sinai

Clinicaltrials.gov

Safety and Efficacy of Secukinumab in Mild Psoriasis

Mild psoriasis not only progresses to moderate-to-severe psoriasis but also precedes systemic inflammation that leads to psoriatic arthritis and cardiovascular comorbidities. By curing mild psoriasis with a...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Novartis

Clinicaltrials.gov

The Role of Food Sensitivity in Psoriasis

Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directed at controlling patients' symptoms. The purpose of this study is to...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Michigan

Clinicaltrials.gov

An Outcomes Study to Determine the Reasons Patients on Biologic...

Patient interviews to evaluate the reason patients discontinue biologic therapy and/or fail to follow up with provider.

Trial Type

Observational

Sponsorship

Janssen Scientific Affairs, LLC

Clinicaltrials.gov

Apremilast as a Direct Treatment for Mild-to-moderate Plaque...

This is a Phase 3, multicenter, randomized, placebo-controlled, double-blind study designed to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with mild to moderate plaque psoriasis....

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Celgene

Clinicaltrials.gov

Secukinumab Therapy for the Treatment of Moderate to Severe Plaque...

This is a phase IV, single-center, open label, single arm study in which a group of 30 subjects with moderate to severe plaque psoriasis will receive secukinumab therapy. Non-invasive imaging with optical...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Novartis

Clinicaltrials.gov

Assess the Potential for Adrenal Suppression and Systemic Drug...

The purpose of this study is to evaluate the potential of DFD-06 to suppress the hypothalamic-pituitary-adrenal (HPA) axis when applied twice daily for 15 days.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Encore Dermatology, Inc.

Clinicaltrials.gov

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric...

This is designated to validate patient-reported outcomes (PRO) measures in itch-specific pediatric skin conditions, such as atopic dermatitis, and examine the ability of a modified stigma instrument to assess...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Regeneron Pharmaceuticals

Clinicaltrials.gov

Videocapillaroscopy Assessment During Systemic Agent Therapy in...

The aim of this study is to determine if videocapillaroscopy could be used as an objective and reliable method to assess psoriasis severity and to document improvement during treatment by measuring changes in...

Trial Type

Observational

Sponsorship

AbbVie

Clinicaltrials.gov

Apremilast in Combination With Clobetasol Spray for the Treatment of...

Researchers want to find out if giving the drug Apremilast in combination with Clobetasol spray can help people clear their moderate to severe plaque psoriasis quicker than if Apremilast is used by itself.

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Washington Dermatology Center

Clinicaltrials.gov

Once-Weekly Oral Aminopterin for the Treatment of Subjects With...

This study evaluates the treatment of psoriasis with aminopterin. Participants will be treated for 14 weeks with either aminopterin or placebo followed. The participants will not know if they are being treated...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

National Institute of Allergy and Infectious Diseases (NIAID)

Clinicaltrials.gov

An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband...

A single center study of 30 patient receiving Narrowband UVB phototherapy three times weekly for 12 weeks. Patients will be evaluated through week 36 to evaluate maintenance of response.

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Psoriasis Treatment Center of Central New Jersey

Clinicaltrials.gov

Study to Evaluate the Safety, Tolerability, Pharmacokinetics,...

This is a multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and immunogenicity of CC-90006 following...

Trial Type

Interventional

Trial Phase

Phase 1

Sponsorship

Celgene

Clinicaltrials.gov

The Role of Bacterial Toxins in Human Skin Disease

Atopic dermatitis and psoriasis are two skin diseases often associated with bacterial infections and inflammation. Studies indicate that skin cells from these patients may have some changes that make these...

Trial Type

Observational

Sponsorship

National Jewish Health

Clinicaltrials.gov

The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis

The purpose of this study is to determine the anti-inflammatory effect of high-dose riboflavin supplementation on chronic plaque psoriasis. Psoriasis is a common chronic skin disorder that affects over 4...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

University of Michigan

From the latest relevant research and Psoriasis expert interviews to personal stories and advice on managing your symptoms, here’s everything about Psoriasis that’s making headlines.

Healio Dermatology

8 stories to read for Psoriasis Action Month

August is Psoriasis Action Month, a national initiative to encourage understanding and enhance education about this common disease. According to the National Psoriasis Foundation, psoriasis affects more than 8 million Americans and roughly 125 million people worldwide. In recognition of Psoriasis Action Month, Healio Dermatology highlights 8 recent articles on developments in research and treatment for psoriasis.

Health.com

4 Things To Know About Scalp Psoriasis, According To Dermatologists

Fun fact: Your skin is the largest organ in your body (that's according to literally everywhere, like the American Academy of Dermatology)—and, as a chronic skin condition, psoriasis can happen anywhere on that organ. But when it shows up on your scalp, it's specifically called scalp psoriasis.

Pharmacy Times

Topical Treatment Options Expanded for Adolescents with Plaque Psoriasis

Officials with the FDA have expanded the indication for LEO Pharma’s calcipotriene and betamethasone dipropionate (Enstilar) foam, 0.005%/0.064%, for the topical treatment of plaque psoriasis to include patients age 12 years and older.

People

17 Celebrities Who’ve Spoken Candidly About Their Psoriasis

Psoriasis is an autoimmune disorder that causes scaly, red, and often itchy patches on the skin. The condition affects millions of Americans — including these celebrities.

DermatologyTimes

Lifting the psoriasis burden

Psoriasis affects more than 8 million Americans and has been associated with a number of comorbidities. Aside from the quality-of-life impact, the disease has an economic impact, as well. Experts say there is a need to capture the true direct and indirect costs to improve outcomes for patients with psoriasis and psoriatic arthritis.

Whether you’re considering participating in a clinical trial or just looking for more information about Psoriasis, we want you to keep you informed about living with Psoriasis, your treatment options, and the clinical trial process.

Connect with others who have Psoriasis to discuss your symptoms, experiences, treatment options, and more.