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Condition-Vitiligo - Hero Image

The autoimmune disease that causes loss of skin color has been costly and hard to treat. But we’re working on giving you new options. Learn about the cutting-edge study treatments being investigated in your neighborhood.


7

treatment options currently available for Vitiligo — none reverse the process of skin depigmentation.

20%

of people with Vitiligo have at least one close relative who also has it. 1

~15%

of people with Vitiligo also have at least one other autoimmune disorder, like rheumatoid arthritis, type 1 diabetes, psoriasis, pernicious anemia, Addison disease, or systemic lupus erythematosus. 2

It's a very exciting time for Vitiligo. We are learning more about the specific autoimmune pathways involved, so we can develop more effective and safe treatments for patients. Our hope is that the clinical studies going on right now will lead to the first oral treatment approved by the FDA.”

Dr. Lisa B. Travis

New York Times Magazine’s “NY Super Doctors”

It's a very exciting time for Vitiligo. We are learning more about the specific autoimmune pathways involved, so we can develop more effective and safe treatments for patients. Our hope is that the clinical studies going on right now will lead to the first oral treatment approved by the FDA.”

Dr. Lisa B. Travis

New York Times Magazine’s “NY Super Doctors”

Vitiligo Clinical Trials

Learn about the newest Vitiligo study treatments now being investigated, including cutting-edge options available to clinical trial participants.

TrialSpark is now recruiting for a trial that tests the effectiveness of a study drug FDA-approved for Rheumatoid Arthritis on Vitiligo symptoms.

Treatments Today

Current Vitiligo treatments can be expensive, time-intensive, and often painful, and are not guaranteed to work. Most treatments on the market aim to create uniformity in skin color, which means patients are often left to choose between not treating their symptoms or using treatments that lighten their skin tone.

7

treatments on the market in 2019 including prescription and over-the-counter.

Cosmetics

Makeup, self-tanners, and skin dyes, which are the safest ways to approach vitiligo. The goal is to camoflauge lost skin color. Note: this process is time consuming as must be repeated every day.

Availablity

OTC; Beauty

Brands

N/A

Drug Class

N/A

Generic

N/A

Diprolene

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions. The strength depends on the form (cream, gel, or ointment) that you use.

Availablity

RX; Prescription

Brands

Diprolene, Luxiq, Sernivo

Drug Class

Topical Corticosteroid

Generic

Betamethasone Topical

webmd.com

Topicort

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Desoximetasone reduces the swelling, itching and redness that can occur in these types of conditions. This medication is a strong corticosteroid.

Availablity

RX; Prescription

Brands

Topicort, Topicort LP

Drug Class

Topical Corticosteroid

Generic

Desoximetasone Topical

drugs.com

Temovate Ointment

This medication is used to treat a variety of skin conditions (e.g., eczema, psoriasis, dermatitis, allergies, rash). Clobetasol reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a very strong (super-high-potency) corticosteroid.

Availablity

RX

Brands

Clobex, Clodan, Cormax, Olux, Olux-E, Temovate

Drug Class

Topical Corticosteroid

Generic

Clobetasol Topical

webmd.com

Tacrolimus Ointment

This form of tacrolimus is used on the skin to treat eczema (atopic dermatitis) in patients who have not responded well to other eczema medications. It works by weakening the skin's immune system, thereby decreasing the allergic reaction and relieving the eczema. Tacrolimus belongs to a class of drugs known as topical calcineurin inhibitors (TCIs).

Availablity

RX; Off Label Use

Brands

Protopic

Drug Class

Topical Calcineurin Inhibitors (TCIs)

Generic

Tacrolimus

webmd.com

Skin Bleaching

Depigmentation, the process of removing the remaining pigment from unaffected skin in order to create uniform, 100% depigmented white skin. This treatment is a rare option, and for individuals who have little pigment left as it is. MBEH or monobenzone is the most commonly used depigmenting agent for vitiligo and the only depigmentation treatment approved by the FDA.

Availablity

RX

Brands

N/A

Drug Class

Benoquin

Generic

Monobenzone

drugs.com

Puva Therapy

PUVA treatment involves making your skin extra sensitive to UVA by means of a psoralen, which is either taken orally as tablets, 2 hours prior to each treatment session, or by the application of a solution, lotion or gel directly onto your skin (sometimes in a bath – bath PUVA).

Availablity

RX; Prescription

Brands

8-Mop, Oxsoralen-Ultra

Drug Class

N/A

Generic

Methoxsalen

wikipedia.org

Narrowband UVB Therapy

Exposure to UVB photo therapy, and does not require the application of Psoralen beforehand. This treatment is more effective on face and neck as compared to PUVA.

Availablity

OTC or Doctor's Office

Brands

N/A

Drug Class

N/A

Generic

N/A

wikipedia.org

Holistic

Some vitamins, minerals, amino acids, and enzymes have been reported to restore skin color in people who have vitiligo, however most have not been thoroughly studied. Ginkgo biloba, an herb, is being investigated further. Early results indicate that the herb may restore skin color and stop vitiligo from worsening.

Availablity

OTC; Wellness

Brands

N/A

Drug Class

N/A

Generic

N/A

A lot of people with vitiligo want better treatments. While existing treatments can be effective, there are so many potential downsides including the time commitment, side effects, expense and remission period.

Erika P

22 years with Vitiligo

A lot of people with vitiligo want better treatments. While existing treatments can be effective, there are so many potential downsides including the time commitment, side effects, expense and remission period.

Erika P

22 years with Vitiligo


Vitiligo In the News

From the latest relevant research and Vitiligo expert interviews to personal stories and advice on managing your symptoms, here’s everything about Vitiligo that’s making headlines.


Vitiligo FAQ

Whether you’re considering participating in a clinical trial or just looking for more information about Vitiligo, we want you to keep you informed about living with Vitiligo, your treatment options, and the clinical trial process.


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See if you qualify for a trial.

New study treatments that may help address your condition are being developed and investigated.

  1. U.S National Library of Medicine, ”Vitiligo,” Genetics Home Reference, (June 11, 2019) Link[1]

  2. U.S National Library of Medicine, ”Vitiligo,” Genetics Home Reference, (June 11, 2019)Link[2]

Updated June 2019