Motion Perception in Individuals With Type 2 Diabetes

Clinical Trial ID: NCT03380832

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Clinicaltrials.gov

Education and Exercise Program for Adults With Type 2 Diabetes

The purpose of this two phase study is to: 1) develop and 2) assess a program titled: Merging Yoga, Occupational Therapy and Nutrition Education (MY-OT-Ed) designed for low income adults with Type 2 Diabetes....

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

American Occupational Therapy Foundation

Clinicaltrials.gov

Food and Education Effects on Diabetes Study

Low-income adults are disproportionately affected by diabetes, experiencing greater rates of diabetes, diabetes-related complications, and mortality. Dietary habits play an important role in achieving and...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

France-Merrick Foundation

Clinicaltrials.gov

Pulsatile Insulin Infusion Therapy in Patients With Type 1 and Type 2...

This study is an open label, prospective, randomised comparative, single center study. In the present study, the impact of a 12-week pulsatile insulin infusion therapy (PIT) with Humulin R 100 from

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Innovative Diabetes Treatment Studies LLC.

Clinicaltrials.gov

Diabetes Prevention Programming for Women With a History of...

The purpose of this study is to offer women with a history of gestational diabetes access to diabetes prevention programming; their children 10 and older can participate.

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Indiana University

Clinicaltrials.gov

Dexcom G6 Intervention Study

The study will assess if Continuous Glucose Monitoring (CGM) represents a better tool to guide healthcare providers in adjusting insulin therapy, by providing a more complete 24-hour assessment of glucose...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Emory University

Clinicaltrials.gov

Tailored Home-Based Exercise Program for Multiple Chronic Conditions

A home-based, tailored, technology-enhanced home-based exercise program (iHBE) using a combination of the integrated mobile technologies (wearable device and phone application) and tailored home-based exercise...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

National Institute of Nursing Research (NINR)

Clinicaltrials.gov

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

This study is designed to evaluate whether epigenetic markers in overweight men with type 1 or type 2 diabetes can be improved with a 3 month lifestyle intervention program.

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Joslin Diabetes Center

Clinicaltrials.gov

Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and...

The investigators aim to determine the effect of suvorexant on subjective total sleep time (TST) in suboptimally controlled Type 2 diabetics with chronic insomnia in a randomized placebo-controlled trial for 3...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Massachusetts General Hospital

Clinicaltrials.gov

Combining Flash Glucose Monitoring and Online Peer Support to Improve...

Currently, Hispanic Spanish-speaking individuals are not receiving culturally appropriate diabetes care. Lack of knowledge impacts several areas of type 2 diabetes (T2D) management, including healthy eating...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

La Trobe University

Clinicaltrials.gov

(R33 Phase) Delish Study: Diabetes Education to Lower Insulin,...

We plan an R33 phase trial in which 120 persons with type 2 diabetes (T2DM) will be randomized (using a 1:1 ratio) to education alone (Ed) on following a carbohydrate restricted diet for T2DM, or this same...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

National Center for Complementary and Integrative Health (NCCIH)

Clinicaltrials.gov

Understanding the Cardiovascular Benefits of the Anti-Diabetes...

To examine the effect of an increase in plasma beta-hydroxy-butyrate (B-OH-B) levels, spanning the physiologic and pharmacologic range (+0.5, +2.0, and +5.0 mmol/L), on: (i) parameters of left ventricular (LV)...

Trial Type

Interventional

Trial Phase

Phase 1

Sponsorship

The University of Texas Health Science Center at San Antonio

Clinicaltrials.gov

Clinic to Community Navigation to Improve Diabetes Outcomes

Background and justification: Nearly 29 million Americans (9.3% of the population) have type 2 Diabetes Mellitus (T2DM) and another 86 million are considered prediabetic, 20-30% of whom will develop diabetes...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Nancy Schoenberg

Clinicaltrials.gov

Recurrent Hypoglycemia in Type 1 Diabetes (Aim 1)

This study will explore the cerebral mechanisms of impaired awareness of hypoglycemia (IAH) in type 1 diabetics following exposure to experimental recurrent hypoglycemia (HG). To induce IAH, patients with T1D...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Minnesota

Clinicaltrials.gov

PRECISION Study: Evaluating the Accuracy of the LabPatch Continuous...

The purpose of this study is to evaluate the accuracy and efficacy of the Cambridge Medical Technologies, LLC LabPatch Continuous Glucose Monitoring (CGM) System compared to a laboratory glucose analyzer (YSI...

Trial Type

Observational

Sponsorship

Cambridge Medical Technologies, LLC

Clinicaltrials.gov

Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved...

This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values)...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

San Diego State University

Clinicaltrials.gov

Validation of Machine Learning Based Personalized Nutrition Algorithm...

This is an initial validation study of the Personal Nutrition Project (PNP) algorithm in a North American population with recently diagnosed Type 2 Diabetes (T2D). This is a 2-stage, single-group feeding study...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

NYU Langone Health

Clinicaltrials.gov

Texting for Diabetes

Diabetes is a common complication of pregnancy that increases risks for both the mother and baby. Poorly controlled diabetes has been associated with very large babies, congenital heart defects, stillbirth,...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

St. Louis University

Clinicaltrials.gov

Insulin Degludec for the Management of Patient With Recurrent...

Given the longer half life of insulin degludec compared to glargine /levemir ,investigators believe that insulin degludec will reduce the rate of recurrent DKA. The investigator will randomize participants to...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Hennepin Healthcare Research Institute.

Clinicaltrials.gov

Role of Canagliflozin on CD34+ Cells in Patients With Type 2 Diabetes

The investigators hypothesize that Cana may be able to improve number and function of CD34+ endothelial progenitor cells. The investigators also propose that this expected cardiovascular benefit is independent...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Janssen Scientific Affairs, LLC

Clinicaltrials.gov

Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye

The treatment in this trial consists of intraocular islet transplantation. A single dose of 1000 - 2000 Islet Equivalents (IEQ)/kg recipient body weight (BW) will be infused into the anterior chamber of the...

Trial Type

Interventional

Trial Phase

Phase 1/Phase 2

Sponsorship

Bascom Palmer Eye Institute

Clinicaltrials.gov

Nitrate Supplementation and Exercise Tolerance in Patients With Type...

The purpose of this study is to use a randomized, double-blind, placebo controlled study design to comprehensively investigate the impact of 8-weeks of dietary nitrate supplementation on skeletal muscle blood...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

American Diabetes Association

Clinicaltrials.gov

Health Literacy Intervention to Improve Diabetes Outcomes Among Rural...

The researchers will conduct a patient-randomized, pragmatic clinical trial among 6 rural PCMHs in Arkansas, targeting individuals with uncontrolled type 2 diabetes. The primary aims are to: 1. test the...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Clinicaltrials.gov

The Relationship Between Advanced Glycation Endproducts and Diabetes

The overall purpose of this COMIRB application is to perform a cross-sectional pilot study to aid in the design of a prospective epidemiologic study for an NIH grant application. The long term goal of this...

Trial Type

Observational

Sponsorship

University of Colorado, Denver

Clinicaltrials.gov

Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and...

Diabetes type two is a debilitating disease that leads to chronic morbidity such as accelerated microvascular disease. Accelerated microvascular disease may produce blindness, end stage renal disease,...

Trial Type

Observational

Sponsorship

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Clinicaltrials.gov

Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With...

Primary Objective: To demonstrate the superiority of once weekly injection of efpeglenatide in comparison to placebo in glycated hemoglobin (HbA1c) change in participants with type 2 diabetes mellitus (T2DM)...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Sanofi

Clinicaltrials.gov

Multicenter Assessment of the Pancreas in Type 1 Diabetes

The overall goal of this research is to develop and validate standard operating procedures (SOP) to assess the human pancreas in individuals with type 1 diabetes (T1D) and other forms of diabetes using...

Trial Type

Observational

Sponsorship

Juvenile Diabetes Research Foundation

Clinicaltrials.gov

Resilience-Based Diabetes Self-Management Education (RB-DSME) for...

African Americans are twice as likely to have type 2 diabetes as non-Hispanic Whites and are less likely to engage in effective diabetes self-management. There is a critical need for intensive lifestyle...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Colorado, Aurora

Clinicaltrials.gov

The Effect of Lysulin on Glycemic Control and Advanced Glycation

The primary objective is to determine whether 12 weeks of treatment with Lysulin, compared to placebo, causes a reduction from baseline in the plasma levels of glucose, hemoglobin A1c (HbA1c) and Advanced...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Juraj Koska

Clinicaltrials.gov

Lowering the Impact of Food Insecurity in African American Adults...

The objective of this protocol is to answer the questions: 1) Within food supplementation options, are mailed stock boxes superior to food vouchers in terms of achieving glycemic control? 2) Is the combination...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Medical College of Wisconsin

Clinicaltrials.gov

Veteran Support and Resources for Diabetes

Patients with diabetes are often challenged by the routine of managing their diabetes, and may experience both stress and medical problems. Diabetes-related medical problems and stress often happen together...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

VA Office of Research and Development

Clinicaltrials.gov

Evaluation of the Impact of Intensive Short-Term Drug Therapy in...

This phase IV study is a prospective open-label multi-center study to investigate the effect of a temporary individualized poly-pharmaceutical De-escalation treatment with the target to regenerate ß-cell...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Innovative Diabetes Treatment Studies LLC.

Clinicaltrials.gov

Taking Action: a Care for Type 2 Diabetes Intervention for Couples

Communal coping consists of the appraisal of a problem as shared and collaboration to manage the problem. Among individuals with type 2 diabetes, self-report, daily diary, and observational measures of...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Carnegie Mellon University

Clinicaltrials.gov

GDM Post Partum Screening

Immediate postpartum screening for diabetes mellitus in women with gestational diabetes The objective of this study is to determine if screening for type 2 diabetes can be done 24 hours after delivery, versus...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Banner University Medical Center

Clinicaltrials.gov

Light, Metabolic Syndrome and Alzheimer's Disease

To test the long term effect of a light treatment on cognition, sleep and metabolism in patients with Mild cognitive impairment (MCI) or mild Alzheimer's disease or related dementia (ADRD).

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Icahn School of Medicine at Mount Sinai

Clinicaltrials.gov

Diabetes Autoimmunity Withdrawn In New Onset and In Established...

TThe study is a prospective, randomized, 52-week double-blind, placebo-controlled, multicenter trial in subjects with T1D followed by a 2-year safety follow-up.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Tolerion, Inc.

Clinicaltrials.gov

Light and the Effect on Metabolic Syndrome and Alzheimer's Disease

This study's main hypothesis is that a delivering a tailored lighting intervention (TLI) will provide a successful means for promoting circadian entrainment and treating metabolic disease and inflammation in...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Icahn School of Medicine at Mount Sinai

Clinicaltrials.gov

Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Sanofi

Clinicaltrials.gov

Fresh Food Farmacy: A Randomized Controlled Trial

This trial investigates the value created by the highly innovative Fresh Food Farmacy (FFF) program at Geisinger Health. The program provides food-insecure diabetics with healthy food for their entire...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Geisinger Clinic

Clinicaltrials.gov

Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to...

This is a two-armed randomized controlled trial (RCT) primarily aimed at determining if application of Cytal Wound Matrix 1-Layer intervention to diabetic foot ulcers shows improved wound closure rates when...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

ACell Inc.

Clinicaltrials.gov

Tu Salud (Your Health) Randomized Control Study in Patients With...

The study seeks to demonstrate the clinical value and user acceptance of the Bluetooth enabled OneTouch Verio® Flex meter (Flex) used in combination with the OneTouch Reveal® Mobile APP to support overall...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

LifeScan

Clinicaltrials.gov

Exercise and the Receptor for Advanced Glycation End Products (RAGE)

This study examines the effects of 12-weeks of aerobic exercise training on the mechanisms driving RAGE-mediated inflammation in type 2 diabetic humans.

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Clinicaltrials.gov

Early MRI Detection of Myocardial Deterioration as a Preventive,...

The purpose of this study is to evaluate the relationship between insulin resistance (IR) and myocardial tissue abnormalities. The study will focus on a patient population, South Asians, with a high prevalence...

Trial Type

Observational

Sponsorship

Stanford University

Clinicaltrials.gov

FreeStyle Libre Flash Glucose Monitoring System Post Approval Study

This is a prospective, multi-center, non-randomized, single-arm, post-approval study of the FreeStyle Libre Flash Glucose Monitoring System intended to characterize the safety of the Libre Flash Glucose...

Trial Type

Observational

Sponsorship

Abbott Diabetes Care

Clinicaltrials.gov

Diabetes Interprofessional Team to Enhance Adherence to Medical Care

The overall goal of this randomized controlled trial is to test the efficacy of DM I-TEAM (Diabetes Interprofessional Team to Enhance Adherence to Medical Care) to reduce emergency department (ED) visits and...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of the Sciences in Philadelphia

Clinicaltrials.gov

Yo Puedo! Diabetes Self-Management Education + mHealth in Mexico City

The aims of this study are: 1. To translate an evidence-based diabetes self-management education (DSME) program, Yo Puedo!, to the cultural norms, expertise of providers, and systems of care in Seguro Popular...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Universidad Iberoamericana

Clinicaltrials.gov

A Psychological-behavioral Intervention for Physical Activity in Type...

The focus of this study is to examine the feasibility, acceptability, and impact of a customized, combined positive psychology and motivational interviewing (PP-MI) health behavior intervention versus a...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Massachusetts General Hospital

Clinicaltrials.gov

Using Multifamily Groups to Improve Self-Management of Type 2 Diabetes

The overall objective of this study is to construct an adaptive intervention that integrates family members and patients as partners in care while promoting diabetes self-management for Mexican Americans with...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of California, Los Angeles

Clinicaltrials.gov

Study to Understand Gaining Access to Blood Glucose Records

This study is a two-arm randomized controlled trial in which participants will receive either the Livongo Health system or iHealth glucose meter for measuring their blood glucose. The study hypothesizes the...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Livongo Health

Clinicaltrials.gov

Glucose Metabolism in Sickle Cell Disease

The purpose of the study is to better understand how the body handles sugars glucose and fats, such as cholesterol and triglycerides in sickle cell disease, and what puts certain persons at risk to develop...

Trial Type

Observational

Sponsorship

University of Illinois at Chicago

Clinicaltrials.gov

Trial to Assess Chelation Therapy 2

Trial to Assess Chelation Therapy 2 (TACT2) is a randomized, double blind controlled factorial clinical trial of edetate disodium-based chelation and high-dose oral vitamins and minerals to prevent recurrent...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Duke Clinical Research Institute