Topical Application of BMX-010 in Subjects With Atopic Dermatitis and Plaque Psoriasis

Clinical Trial ID: NCT03381625


This is a randomized, placebo-controlled Phase 2 trial consisting of up to 300 subjects with either psoriasis or atopic dermatitis. In this trial BMX-010 will be topically applied twice daily for up to 28 days.

This is a Phase 2, randomized, multicenter, placebo-controlled study sponsored by BioMimetix JV, LLC (BMX). It is a double-blind parallel cohort study designed to determine the safety and efficacy of BMX-010 (0.03%) relative to Placebo in subjects with atopic dermatitis and psoriasis. Subjects will be queried regarding adverse events (AEs) and concomitant medication usage.


Inclusion Criteria: - Diagnosis of either atopic dermatitis or psoriasis with mild to moderate lesions involving 1% - 25% of total body surface area - Candidate for topical treatment of atopic dermatitis or psoriasis - Negative pregnancy test for females of childbearing potential Exclusion Criteria: - Systemic pharmacotherapy or phototherapy for treatment of atopic dermatitis or psoriasis - Erythrodermic, guttate or generalized pustular psoriasis - Treatment of systemic retinoids, corticosteroids or immunosuppressive agents within 4 weeks of baseline visit - Treatment with high potency topical steroids, vitamin D analogs, keratolytics, coal tar, phototherapy, calcineurin inhibitors, or antihistamines within 2 weeks of baseline visit - UV or Dead Sea therapy within 4 weeks of baseline visit - Treatment with a biologic agent (monoclonal antibody) within 30 days or 5 times its circulating half-life (whichever is longer) prior to baseline visit - Atopic dermatitis triggered by environmental allergen or irritant - Contact dermatitis or drug-induced skin reactions - Systemic or skin infection requiring antimicrobial therapy - Systemic chemotherapy or radiotherapy within 4 weeks of baseline visit - Immunocompromise of any cause - Pregnancy, lactation or inadequate contraception - Active drug or alcohol dependence - Significant acute or chronic medical, neurological or psychiatric illness that would compromise subject's safety

  • Start Date


  • Last Updated


  • Sponsor

    BioMimetix JV, LLC

  • Condition Name

    Atopic Dermatitis

Learn about this trial.

Check the eligibility requirements, study details, and more.

Related Trials

Different trials target different symptoms, condition types, and patients. Learn more about other emergeing treatments being investigated now.