Bleach vs. Bubbles: Assessing the Impact of the Bathroom Environment on Eczema

Clinical Trial ID: NCT03619161

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Clinicaltrials.gov

Improvement of Short Term Outcome of Mild to Moderate Atopic...

This trial is a single-center two arm, open label observational prospective study, that will evaluate the safety and efficacy of crisaborole ointment, 2% alone compared to a combination therapy of crisaborole...

Trial Type

Observational

Sponsorship

Pfizer

Clinicaltrials.gov

The Role of Bathing Additives in the Treatment of Pediatric Atopic...

To evaluate the efficacy of water bath, water + bleach, and water + vinegar (acetic acid) in the treatment of atopic dermatitis (eczema)

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

HealthPartners Institute

Clinicaltrials.gov

A Community-based Assessment of Skin Care, Allergies, and Eczema

Atopic dermatitis (AD) affects over 9 million children in the U.S. and often heralds the development of asthma, food allergy, skin infections and neurodevelopmental disorders. Recent advances identify skin...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

Duke University

Clinicaltrials.gov

A Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the...

This phase 2b study is designed to evaluate the safety and efficacy of tezepelumab as a monotherapy and explore its efficacy as adjunct therapy in subjects with moderate-to-severe AD.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

AstraZeneca

Clinicaltrials.gov

Efficacy and Safety of MEDI3506 in Adult Subjects With Atopic...

This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult subjects with Atopic Dermatitis.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

AstraZeneca

Clinicaltrials.gov

Scratch Behavior Under Standard of Care

Wrist-worn accelerometers and associated data analysis platforms will provide quantitative and qualitative knowledge regarding the action of scratching and sleep quantity in a symptomatic Atopic Dermatitis...

Trial Type

Observational

Sponsorship

Boston University

Clinicaltrials.gov

Immunogenetic Profiling of Dupilumab for the Treatment of Atopic...

This is a single-arm, open-label study to examine the effect of dupilumab on the immunologic and genetic environment within atopic dermatitis skin lesions.

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Sanofi

Clinicaltrials.gov

A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric...

The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).

Trial Type

Interventional

Trial Phase

Phase 1

Sponsorship

Incyte Corporation

Clinicaltrials.gov

Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema,...

This is a tissue, urine, and blood banking protocol for cutaneous t-cell lymphoma (CTCL), eczema, and atopic dermatitis patients for current and future research.

Trial Type

Observational

Sponsorship

University of Pittsburgh

Clinicaltrials.gov

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and...

This is a pragmatic, randomized, controlled, equivalency trial. This 12-month trial will evaluate the impact of an online, team-based connected health (TCH) model for management of atopic dermatitis (AD) as...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Clinicaltrials.gov

Study of the Safety, Tolerability and Efficacy of BTX 1204 in...

This is a randomized, double-blind, vehicle-controlled, Phase 2 study in subjects with moderate AD.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Botanix Pharmaceuticals

Clinicaltrials.gov

The Impact of Dupilumab on Quality of Life in Moderate to Severe...

This is a single-arm, open-label study, which will examine the effect of dupilumab on quality of life in atopic dermatitis patients.

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Regeneron Pharmaceuticals

Clinicaltrials.gov

Etiology of Eczema Herpeticum (EH)

Atopic dermatitis, also called eczema, is a disease with dry, scaly, itchy skin. Those with atopic dermatitis may have complications from skin infections such as eczema herpeticum after herpes simplex virus...

Trial Type

Observational

Sponsorship

Atopic Dermatitis Research Network

Clinicaltrials.gov

A Study to Evaluate Long-Term Maintenance Treatment With Once Daily...

This study will evaluate crisaborole therapy once daily (QD) as a long-term topical maintenance therapy for the reduction of flare in responders to crisaborole twice daily (BID) treatment.

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Pfizer

Clinicaltrials.gov

Evaluating the Effect of Bathing Additives in Atopic Dermatitis

This proposed project will be an open-label, split-arm, randomized controlled pilot study. Up to 60 patients diagnosed with atopic dermatitis (eczema) will be enrolled in the study. The purpose of this study...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Arizona

Clinicaltrials.gov

Efficacy and Safety of Orally Administered DS107 in Adult Patients...

The objective of this study is to compare the efficacy and safety of orally administered DS107 (2g) versus placebo in the treatment of moderate to severe Atopic Dermatitis (AD). Oral DS107/Placebo capsules...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

DS Biopharma

Clinicaltrials.gov

Evaluating the Effects of Cleansers on the Skin

This will be a single visit study that will take approximately 2 hours. Up to 50 subjects (up to 25 healthy subjects, and up to 25 subjects with AD) from BUMC dermatology clinics will be enrolled in this study...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Arizona

Clinicaltrials.gov

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate...

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Bausch Health Americas, Inc.

Clinicaltrials.gov

A Pilot Study to Explore the Role of Gut Flora in Eczema

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding eczema.

Trial Type

Observational [Patient Registry]

Sponsorship

ProgenaBiome

Clinicaltrials.gov

SAR231893-LPS15497- "Dupilumab Effect on Sleep in AD Patients"

Primary Objective: To evaluate the effect of dupilumab on sleep quality in adult patients with moderate to severe atopic dermatitis (AD) Secondary Objectives: To evaluate the effect of dupilumab on objective...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Regeneron Pharmaceuticals

Clinicaltrials.gov

A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI...

This 4-week study will evaluate the safety and efficacy of crisaborole ointment 2%; crisaborole vehicle; topical corticosteroid and topical calcineurin inhibitor, applied twice daily (BID) in subjects who are...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Pfizer

Clinicaltrials.gov

Monitoring Of Scratch Via Accelerometry In Children

Sleep sensors, wrist worn accelerometers, polysomnography (PSG), and associated data analysis platforms would provide quantitative and qualitative knowledge regarding the action of scratching and sleep...

Trial Type

Observational

Sponsorship

Boston University

Clinicaltrials.gov

Clobetasol Topical Oil for Children With Moderate to Severe Atopic...

Open-Label Study designed to evaluate the HPA axis suppression potential of Clobetasol Topical Oil and pharmacokinetic safety / systemic exposure to clobetasol when Clobetasol Topical Oil is applied to...

Trial Type

Interventional

Trial Phase

Phase 1/Phase 2

Sponsorship

Covance

Clinicaltrials.gov

Steroid-reducing Effects of Crisaborole

Atopic dermatitis, or eczema, is a chronic skin condition affecting many children. Crisaborole is a non-steroid topical medication which is FDA approved for children aged 2 and older for eczema. This research...

Trial Type

Interventional

Trial Phase

Phase 4

Sponsorship

Pfizer

Clinicaltrials.gov

Bone Health in Patients With Atopic Dermatitis

This study examines the bone health in children with atopic dermatitis

Trial Type

Observational

Sponsorship

Pediatric Dermatology Research Alliance

Clinicaltrials.gov

JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With...

This is a randomized, double blind, placebo controlled, parallel group, Phase 3 study to evaluate the efficacy and safety of PF 04965842 in adolescent participants 12 to <18 years of age with moderate to...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Pfizer

Clinicaltrials.gov

Wearable Skin Sensors to Assess Nocturnal Scratch Behavior

Pilot study of flexible and wearable sensor to monitor nocturnal scratching behavior

Trial Type

Observational

Sponsorship

Pfizer

Clinicaltrials.gov

ASPIRE: PROs & Caregiver Burden in Children With Atopic Dermatitis

This is an open-label, randomized, cross-sectional study to monitor the effects of crisaborole and tacrolimus 0.03% on patient-reported outcomes and caregiver burden in children (ages 5 to 12 years, inclusive)...

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

University of Rochester

Clinicaltrials.gov

A Study Investigating the Efficacy, Safety, and PK Profile of ANB020...

This study is designed to evaluate the efficacy, safety, and pharmacokinetic (PK) profiles of multiple doses of ANB020 in subjects with atopic dermatitis (AD).

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

AnaptysBio, Inc.

Clinicaltrials.gov

Efficacy and Safety of IDP-124 Lotion

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects

Trial Type

Interventional

Trial Phase

Phase 3

Sponsorship

Bausch Health Americas, Inc.

Clinicaltrials.gov

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Atopic dermatitis (AD), also known as eczema, is the most common inflammatory skin disorder of children, affecting 10-20% of children and 1-2% of adults. This skin disorder can be associated with unbearable...

Trial Type

Observational

Sponsorship

Icahn School of Medicine at Mount Sinai

Clinicaltrials.gov

10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have...

This study will examine the risk of systemic malignancies in pediatric patients with atopic dermatitis exposed to Elidel 1% cream.

Trial Type

Observational

Sponsorship

Clinical Research Computing Unit (University of Pennsylvania)

Clinicaltrials.gov

A Study to Assess the Safety and Efficacy of ZPL389 With TCS/TCI in...

This study is planned to assess long term safety and efficacy of ZPL389 by continuing 2 year treatment in atopic dermatitis patients.

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Novartis Pharmaceuticals