We are a tech-enabled drug development partner.

TrialSpark brings treatments to patients faster and more efficiently by reimagining the clinical trial process.

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TrialSpark runs end-to-end clinical trials as a technology-driven alternative to a traditional CRO. TrialSpark partners with community physicians to enable broader participation in clinical trials and is powered by a standardized technology platform for data collection, management, and analysis. TrialSpark is able to unlock the 99% of patients and clinicians who traditionally haven't been able to participate in trials, boosting recruitment rates and democratizing access.

The path to faster COVID-19 trials

Learn more about our partnership with tech entrepreneur Sam Altman and physician-scientist Mark Fishman.

Our end-to-end trial capabilities

  • Sponsor 2 - Clinical Strategy

    Full-Service Clinical Strategy

    Our experienced leadership team partnered with our network of physicians and patients allows us to provide unique insights into protocol design and creates opportunities to innovate within your pipeline.

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    Comprehensive Trial Operations

    Centralized coordinator staffing and clinical project management streamline your study, preventing variability-based errors and increasing protocol adherence.

  • Sponsor 2 - Data Driven Site Selection

    Data-Driven Site Network

    We identify and create the ideal sites for your protocol through robust querying of our EHR database and bespoke network build-outs. These queries directly inform feasibility estimates to generate accurate projections.

  • Sponsors 2 - Data Capture

    Data Capture and Analysis

    Pilot, our Direct Data Capture (DDC) platform, integrates CTMS, eSource and EDC all in one, eliminating transcription delays and enabling real-time source data verification.

  • Sponsors 2 - Recruitment

    Patient Centric Research

    Our model optimizes for patient experience. We improve access by bringing trials to patient communities, and tailor direct touchpoints to support patients from enrollment through completion.


TrialSpark’s existing network includes 900 physicians and 4.1 million patient lives.


TrialSpark’s average screen failure rate is 50% lower than the US standard for comparable studies.


TrialSpark enrolls an average of 1.9x faster than comparable studies.

Bring your new treatments to more patients in less time

Today’s clinical trials hold the key to tomorrow’s life-changing treatments. Make your clinical trials available at more sites and to more patients all over the country.

Select Partners

We partner with the best. Join other life sciences companies bringing life-changing treatments to the market faster with TrialSpark.

Sponsor Logo - Pfizer
Sponsor Logo - Novartis
Sponsor Logo - Sanofi
Sponsor Logo - AstraZeneca
The amount of planning and analysis that goes into all of TrialSpark’s decision-making is truly unique. We just don’t see other partners with a composite EHR database to mine, real-world physicians to call, and an in-house clinical team to consult.

Clinical Development Lead


TrialSpark expands access to new treatments for populations that have never been exposed to clinical trials as a treatment option. They deliver faster recruitment and diversify overall enrollment to ensure our therapies work for everyone.