Evaluation of Multi-Organ Metabolism and Perfusion in NAFLD by Total Body Dynamic PET Scan on EXPLORER

Clinical Trial ID: NCT04165343

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Clinicaltrials.gov

Curcumin for Pediatric Nonalcoholic Fatty Liver Disease

This is a single-center, randomized, double-blinded, placebo-controlled, parallel treatment groups phase 2a study of curcumin for pediatric nonalcoholic fatty liver disease (NAFLD).

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Thorne Research Inc.

Clinicaltrials.gov

Vertical Sleeve Gastrectomy and Lifestyle Modification for the...

Participants meeting study entry criteria are randomized with equal probability to one of two study groups: (1) Lifestyle modification or (2) Vertical Sleeve Gastrectomy (VSG) with Iifestyle modification,...

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Minnesota

Clinicaltrials.gov

A Study to Assess the Efficacy, Safety and Tolerability of Oral LPCN...

This is a Phase 2, randomized, double-blind, placebo controlled, three arm study in adult men with biopsy confirmed NASH. The study is aimed at evaluating efficacy and tolerability of LPCN 1144 in adult men...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

Lipocine Inc.

Clinicaltrials.gov

Spironolactone Therapy In Young Women With NASH

Nonalcoholic steatohepatitis (NASH), or fat-related liver inflammation and scarring is projected to be the leading cause of cirrhosis in the United States (U.S.) within the next few years. Women are at...

Trial Type

Interventional

Trial Phase

Phase 1/Phase 2

Sponsorship

Monika Sarkar, MD

Clinicaltrials.gov

Non-Invasive Evaluation of Liver Steatosis, Inflammation and Fibrosis

The goal of this study is to evaluate non-invasive imaging techniques for determining liver steatosis (fat), inflammation (abnormal tissue swelling), and fibrosis (abnormal tissue scarring).In addition, the...

Trial Type

Observational

Sponsorship

University of California, Davis

Clinicaltrials.gov

Hepatic Energy Fluxes in NASH and NAS Patients

Diseases along the nonalcoholic fatty liver disease spectrum, which are tightly coupled to the obesity epidemic, are soon to become the commonest indication for liver transplantation in the United States....

Trial Type

Interventional

Trial Phase

N/A

Sponsorship

University of Minnesota

Clinicaltrials.gov

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in...

A Phase 2 study with 4 treatment groups of two differing doses and matched placebos designed to evaluate the safety (including hepatic safety), tolerability and pharmacodynamic effects of two dose levels of...

Trial Type

Interventional

Trial Phase

Phase 2

Sponsorship

MedImmune LLC